Mark P. Beenhakker

Spike-wave discharges reflect widespread, but non-uniform, cortical hypersynchrony during immobility

This study investigates spike-wave discharges (SWDs) in mice, showing they cause widespread cortical hypersynchrony, with varying effects across brain regions and potential behavioral influences.

Midline Thalamic Neurons Show Early Hypersynchrony During Absence Seizures in Mouse Models

The paper identifies early hypersynchrony in midline thalamic neurons during absence seizures in mouse models and shows that disrupting this activity stops seizures.

Adenosine A2A and A2B receptor signaling in neurons promotes glucose and fatty acid release in the postprandial state

Respiratory Alkalosis Provokes Spike-Wave Discharges in Seizure- Prone Rats

The paper shows that hyperventilation triggers seizures in rats by activating pH-sensitive neurons in the thalamus.

Extracellular cues accelerate neurogenesis of induced pluripotent stem cell derived neurons

This study accelerates and standardizes the maturation of iPSC-derived neurons by optimizing extracellular cues, resulting in synchronized neurogenesis and earlier calretinin expression.

Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic network oscillations

The paper shows that blocking both GAT1 and GAT3 suppresses thalamocortical oscillations, revealing nonlinear regulation of T-type calcium channels by GABAB receptor activity.