Author

George J. Farmer

University of Nottingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. Robert LaneiD· 1 shared Jacqueline R. Glenn· 1 shared Jana SheniD· 1 shared Joseph ClaytoniD· 1 shared Lei ShiiD· 1 shared Lidiya StavitskayaiD· 1 shared Meritxell CanalsiD· 1 shared Shailesh N. MistryiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

J. Robert LaneORCID

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1 paper

Recent·Most cited

Membrane Permeability Drives the Extreme Potency of Fentanyl but not Isotonitazene

Joseph Clayton, George J. Farmer, Jacqueline R. Glenn, Shailesh N. Mistry, J. Robert Lane, Lei Shi, Lidiya Stavitskaya, Meritxell Canals, Jana Shen

This study investigates how membrane permeability affects the potency of fentanyl and isotonitazene, finding that fentanyl's extreme potency may be due to its ability to accumulate in membranes and repartition to bind receptors.

bioRxiv · Jul 22, 2025 · PreprintBiophysics