In Vivo Dual RNA-Seq uncovers key toxin-like effectors of epithelial barrier disruption and tissue colonization by an extracellular bacterial pathogen
Alexandre Giraud-Gatineau, Georges Haustant, Marc Monot, Mathieu Picardeau, Nadia Benaroudj
This study uses dual RNA-Seq to identify bacterial effectors that disrupt host cell junctions and enable Leptospira colonization by modulating calcium signaling.
bioRxiv · Apr 4, 2025 · PreprintMicrobiology