Remodelled cholesteryl ester enriched lipid droplets fuel flavivirus morphogenesis
Adrianna Banducci-Karp, Sophie Brixton, Pranav N. M. Shah, Mingyuan Li, Georgina Fisher, Joey Riepsaame, Raman Dhaliwal, Katie L. Holden, Edward Drydale, James Bancroft, Charlotte E. Melia, Gathsaurie Neelika Malavige, Sumana Sanyal
This study identifies cholesteryl ester-enriched lipid droplets as critical host components required for flavivirus infection and shows their role in viral morphogenesis.
bioRxiv · Jun 7, 2025 · PreprintCell Biology