Tethering Piezo channels to the actin cytoskeleton for mechanogating via the E-cadherin-β-catenin mechanotransduction complex
Jing Wang, Jinghui Jiang, Xuzhong Yang, Gewei Zhou, Li Wang, Bailong Xiao
This paper identifies how Piezo1 channels are tethered to the actin cytoskeleton via the E-cadherin-β-catenin complex, enabling mechanogating through direct force transmission.
Cell Reports · Feb 1, 2022Peer-reviewedNeuroscience