Author

Gianna Bloye

1Department of Haematology, University College London Cancer Institute, London, United Kingdom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam TurnaiD· 1 shared Adele K. FieldingiD· 1 shared Alejandro GutierreziD· 1 shared David O’ConnoriD· 1 shared James O. J. DaviesiD· 1 shared Jim R. HughesiD· 1 shared Joana R. CostaiD· 1 shared Jonas DemeulemeesteriD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam TurnaORCID

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1 paper

Recent·Most cited

Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, , Marc R. Mansour

The paper identifies a novel mechanism where focal deletions of an intronic element in FTO lead to IRX3 activation in T-ALL through enhancer hijacking.

bioRxiv · Feb 6, 2024Cancer Biology