Author

Tanya Rapoz-D’Silva

University College LondonORCID 0000-0001-7194-3522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam TurňaiD· 2 shared David O’ConnoriD· 2 shared Jonas DemeulemeesteriD· 2 shared Lingyi Wang· 2 shared Marc R. MansouriD· 2 shared Adele Kay FieldingiD· 1 shared Alejandro GutiérreziD· 1 shared Alfred Thomas LookiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Adam TurňaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 16, 2025

MYC-induced oncogenesis is dependent on acidic patches within its N-terminal intrinsically disordered domain.

Víctor Llombart, David O’Connor, Jonas Demeulemeester…·Marc R. Mansour

This study identifies acidic patches in the MYC N-terminal disordered domain essential for oncogenesis and chromatin interaction, offering new therapeutic targets.

DOI 10.1101/2025.06.16.659507

humanexperimental assay

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Cancer BiologyBloodPeer-reviewedSep 24, 2024

Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah…·Marc R. Mansour

The paper identifies a novel mechanism where focal deletions of an intronic element in FTO lead to IRX3 activation in T-ALL through enhancer hijacking.

10 citations

humanDNA methylation

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