Lipid lowering alone fails to limit atherosclerosis progression and neutrophilic inflammation in middle-aged mice
Olivia J. Gannon, Allison Rahtes, Jesse L. Bonin, Ignacia Salfate del Rio, Jessica Partridge, Sayeed Khan, Ariana Nobles, Gideon R. Covert, Amber Bahr, Ramon Bossardi Ramos, Katherine C. MacNamara, Gabrielle Fredman
This study shows that lipid lowering in middle-aged mice fails to reduce atherosclerosis progression and neutrophilic inflammation, unlike in young mice.
bioRxiv · Nov 4, 2025 · PreprintImmunology