Joanne N. Engel

Mechanofiltration Enables High-Throughput Measurements of Bacterial Cell Mechanics

This paper introduces mechanofiltration, a high-throughput method to measure bacterial cell mechanics using standard lab equipment, showing it accurately detects changes in cell stiffness across genetic and environmental conditions.

The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking

This study identifies two short linear motifs in Chlamydia effector IncE that reprogram host vesicle trafficking to support bacterial replication.

The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners

This paper identifies the interaction between Chlamydia trachomatis effector Tri1 and host TRAF7, showing Tri1 displaces TRAF7's native binding partners to alter its signaling during infection.

The Chlamydia trachomatis secreted effector CebN targets nucleoporins and Rae1 to antagonize STAT1 nuclear import

This study identifies CebN, a Chlamydia trachomatis effector that targets nucleoporins and Rae1 to disrupt STAT1 nuclear import, aiding bacterial survival.

Spatial control of sensory adaptation modulates mechanosensing in Pseudomonas aeruginosa

This study identifies a spatial mechanism of sensory adaptation in Pseudomonas aeruginosa, revealing how enzyme localization modulates mechanosensing and virulence.