NeurosciencebioRxivPreprint
Functional coupling of TRPM2 and NMDARs exacerbates excitotoxicity in ischemic brain injury
Pengyu Zong, Jianlin Feng, Zhichao Yue…·Lixia Yue
The paper identifies a novel mechanism where TRPM2 interacts with NMDARs to enhance excitotoxicity in ischemic stroke and develops a peptide to block this interaction, offering a new therapeutic strategy.
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