The chromatin conformation landscape of Alzheimer's disease
Raffaella Nativio, Y Lan, Grace D. Donahue, Oksana Shcherbakova, N Barnett, KR Titus, H Chandrashekar, Jennifer E. Phillips‐Cremins, Nancy M. Bonini, Shelley L. Berger
The paper investigates chromatin conformation changes in Alzheimer's disease, finding loss of genomic loops and CTCF dysfunction linked to neurodegeneration.
bioRxiv · Apr 9, 2024 · PreprintNeuroscience