Author

Grace Freke

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anu I. SironeniD· 1 shared Avishek PrasaiiD· 1 shared Dagan JenkinsiD· 1 shared Emma PeskettiD· 1 shared Gaurav D. DiwaniD· 1 shared Georg OttoiD· 1 shared Hannah M. MitchisoniD· 1 shared Jacqueline S. Y. Lim· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anu I. SironenORCID

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2 papers

Recent·Most cited

HYDIN variants cause primary ciliary dyskinesia in the Finnish population

Thomas Burgoyne, Mahmoud R. Fassad, Rüdiger Schultz, Varpu Elenius, Jacqueline S. Y. Lim, Grace Freke, Ranjit Rai, Mai A Mohammed, Hannah M. Mitchison, Anu I. Sironen

This study identifies HYDIN variants as a cause of primary ciliary dyskinesia in the Finnish population, showing their clinical and functional impact.

Pediatric Pulmonology · Sep 18, 2024Peer-reviewedGenetic & Genomic Medicine

De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of Bbs1.

Grace Freke, Tiago Martins, Rosalind Jane Davies, Tina Beyer, Marian Seda, Emma Peskett, Naila Haq, Avishek Prasai, Georg Otto, Jeshmi Jeyabalan, Víctor Hernández-Hernández, Gaurav D. Diwan, Robert B. Russell, Marius Ueffing, Martina Huranová, , Dagan Jenkins

The paper investigates the role of BBS1 in suppressing mesenchymal cell identities in epithelial cells, showing clonal variability and dysregulation of EMT genes across tissues.

Cells · Nov 20, 2023Peer-reviewedGenetics