Author

Georg Otto

University College LondonORCID 0000-0002-3929-948XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Philip L. BealesiD· 2 shared Alastair Morris KilpatrickiD· 1 shared Avishek PrasaiiD· 1 shared Chiara Bacchelli· 1 shared Cristina Benito· 1 shared Dagan JenkinsiD· 1 shared Daniel KelbermaniD· 1 shared Emma PeskettiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Philip L. BealesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of Bbs1.

Grace Freke, Tiago Martins, Rosalind Jane Davies, Tina Beyer, Marian Seda, Emma Peskett, Naila Haq, Avishek Prasai, Georg Otto, Jeshmi Jeyabalan, Víctor Hernández-Hernández, Gaurav D. Diwan, Robert B. Russell, Marius Ueffing, Martina Huranová, , Dagan Jenkins

The paper investigates the role of BBS1 in suppressing mesenchymal cell identities in epithelial cells, showing clonal variability and dysregulation of EMT genes across tissues.

Cells · Nov 20, 2023Peer-reviewedGenetics

MOPower: an R-shiny application for the simulation and power calculation of multi-omics studies.

Hamzah Syed, Georg Otto, Daniel Kelberman, Chiara Bacchelli, Philip L. Beales

MOPower is an R-shiny application that simulates multi-omics data and calculates power for association studies using various integration methods.

bioRxiv · Dec 19, 2021 · PreprintBioinformatics

Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

Laura J. Wagstaff, Jose Antonio Gomez-Sanchez, Shaline V. Fazal, Georg Otto, Alastair Morris Kilpatrick, Kirolos G. F. T. Michael, Liam Y.N. Wong, Ki Hwan Ma, Mark Turmaine, John P. Svaren, Tessa Gordon, Peter Arthur‐Farraj, Sergio Velasco-Avilés, Hugo Cabedo, Cristina Benito, , Kristján R. Jessen

The paper shows that restoring Schwann cell c-Jun rescues nerve regeneration failures in aging and chronic denervation by enhancing regenerative support.

eLife · Jan 21, 2021Peer-reviewedNeuroscience