De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of Bbs1.
Grace Freke, Tiago Martins, Rosalind Jane Davies, Tina Beyer, Marian Seda, Emma Peskett, Naila Haq, Avishek Prasai, Georg Otto, Jeshmi Jeyabalan, Víctor Hernández-Hernández, Gaurav D. Diwan, Robert B. Russell, Marius Ueffing, Martina Huranová, , Dagan Jenkins
The paper investigates the role of BBS1 in suppressing mesenchymal cell identities in epithelial cells, showing clonal variability and dysregulation of EMT genes across tissues.
Cells · Nov 20, 2023Peer-reviewedGenetics