Jiasheng Zhang

This study identifies PDK4 as a regulator of TGF{beta}-mediated SMC contractility, showing that reducing PDK4 limits atherosclerosis by preserving SMC phenotype.

This study identifies DCBLD2 signal sequence-derived peptides that enhance VEGFR2 signaling and angiogenesis, suggesting therapeutic potential for vascular disorders.

This study identifies HOIL-1 as an atypical E3 ligase that protects the ribosome during nutrient stress, revealing a new signaling pathway involved in cell fate decisions.

This study shows TCF7L2 promotes VSMC differentiation and inhibits proliferation, reducing intimal hyperplasia in mice with LRP6 mutations.