Author

Guangyu Sheng

Shanghai University of Traditional Chinese Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Bo TaniD· 1 shared Chaoyang YeiD· 1 shared Di HuangiD· 1 shared Dong‐Ping CheniD· 1 shared Feng YangiD· 1 shared Junyan LiniD· 1 shared Ming WuiD· 1 shared Pinglan LiniD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Bo TanORCID

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1 paper

Recent·Most cited

Epigenetically silencing gluconeogenic enzyme PCK1 by EZH2 promotes renal tubulointerstitial fibrosis

Ming Wu, Dong‐Ping Chen, Yanzhe Wang, Pinglan Lin, Feng Yang, Junyan Lin, Bo Tan, Guangyu Sheng, Xuejun Yang, Di Huang, Chaoyang Ye

This study shows that EZH2 epigenetically suppresses PCK1, a gluconeogenic enzyme, promoting renal fibrosis, and that restoring PCK1 reduces fibrosis in CKD models.

bioRxiv · Oct 31, 2022 · PreprintMolecular Biology