Feng Yang

This study identifies phosphorylation sites in 17β-HSD1 and develops cell-penetrating peptides that inhibit its activity, reducing breast cancer cell proliferation and tumor growth.

The paper assesses genetic and transcriptomic diversity in 17 Phaeodactylum tricornutum accessions, revealing increased genetic diversity and novel clades, while showing no link between sampling year and diversity loss.

This study shows that EZH2 epigenetically suppresses PCK1, a gluconeogenic enzyme, promoting renal fibrosis, and that restoring PCK1 reduces fibrosis in CKD models.