Author

Yanzhe Wang

Shanghai University of Traditional Chinese MedicineORCID 0009-0006-9990-4326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Chaoyang YeiD· 2 shared Di HuangiD· 2 shared Ming WuiD· 2 shared Bo TaniD· 1 shared Dong‐Ping CheniD· 1 shared Feng YangiD· 1 shared Guangyu Sheng· 1 shared Junyan LiniD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Chaoyang YeORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 29, 2023

Triptolide ameliorates renal tubulointerstitial fibrosis through EZH2

Yanzhe Wang, Ying Jing, Di Huang…·Chaoyang Ye

This study shows triptolide reduces renal fibrosis by inhibiting EZH2 in obstructive kidney disease models.

DOI 10.1101/2023.01.29.526092

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 31, 2022

Epigenetically silencing gluconeogenic enzyme PCK1 by EZH2 promotes renal tubulointerstitial fibrosis

Ming Wu, Dong‐Ping Chen, Yanzhe Wang…·Chaoyang Ye

This study shows that EZH2 epigenetically suppresses PCK1, a gluconeogenic enzyme, promoting renal fibrosis, and that restoring PCK1 reduces fibrosis in CKD models.

2 citations

mousebulk RNA-seq

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