Author

Guihong Lai

Sun Yat-sen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Haiqing Zeng· 1 shared Jia‐Xing YueiD· 1 shared Jing LiiD· 1 shared Li Zhang· 1 shared Ludong YangiD· 1 shared Yan ShuaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

Haiqing Zeng

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1 paper

Recent·Most cited

Genetic background diversifies mutational paths but converges on membrane depolarization for bleomycin resistance in yeast

Yan Shuai, Guihong Lai, Ludong Yang, Haiqing Zeng, Li Zhang, Jia‐Xing Yue, Jing Li

This study shows that while genetic background shapes mutational paths to bleomycin resistance in yeast, all backgrounds converge on membrane depolarization via PMA1 and PTK2 mutations.

bioRxiv · Aug 1, 2026 · PreprintGenetics