Yan Shuai

This paper introduces TeloXplorer, a framework for analyzing telomere features in long-read data, showing how telomere diversity is inherited across species and populations.

This study shows that while genetic background shapes mutational paths to bleomycin resistance in yeast, all backgrounds converge on membrane depolarization via PMA1 and PTK2 mutations.

The paper analyzes 3562 human and animal papillomavirus genomes to uncover genomic diversity, evolutionary patterns, and pathogenicity drivers, identifying key mutations and variants associated with cancer risk and prognosis.