Ludong Yang

This paper introduces TeloXplorer, a framework for analyzing telomere features in long-read data, showing how telomere diversity is inherited across species and populations.

This study shows that while genetic background shapes mutational paths to bleomycin resistance in yeast, all backgrounds converge on membrane depolarization via PMA1 and PTK2 mutations.

This study presents a chromosome-anchored genome assembly of Asymmetron lucayanum, revealing genome architecture and gene evolution in cephalochordates.

This study identifies a novel feedback system regulating Cdk function through Spo12, a small disordered protein that inhibits PP2A, and shows its role in enhancing cell proliferation in fission yeast.

The paper analyzes 3562 human and animal papillomavirus genomes to uncover genomic diversity, evolutionary patterns, and pathogenicity drivers, identifying key mutations and variants associated with cancer risk and prognosis.

NanoTrans provides a comprehensive computational framework for analyzing Nanopore direct-RNA sequencing data, covering isoform clustering, poly(A) tail length estimation, RNA modification profiling, and fusion gene detection across multiple organisms.

This study characterizes the temporal landscape of A-to-I editing in mouse retina development and shows its dynamic interplay with splicing and translation.

riboCIRC provides a database of translatable circRNAs with computational predictions, experimental validations, and cross-species conservation analysis.