Critical role of cell competition in gliomagenesis
Ying Jiang, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun Kim, Guoxin Zhang, Zihao Liu, Zhenqiang He, Lindsey Anne Dudley, Kunal S. Patel, Godfrey A. Dzhivhuho, Sam Crowl, Piotr Przanowski, Luisa Quesada Camacho, Sijie Hao, , Hui Zong
This study identifies cell competition as a key driver of gliomagenesis by showing that pre-malignant OPCs outcompete wildtype cells, and inhibiting this process reduces tumor growth.
bioRxiv · Jan 16, 2026 · PreprintCancer Biology