Ping Liu

stLFRsv detects structural variations using co-barcoded long reads, achieving 74.2% precision and 22.3% recall for deletions in HG002/NA24385.

This study creates the first single-cell brain atlas of domestic pigs, identifies cell types and their spatial distribution, and compares them with other species to reveal evolutionary and disease-related insights.

The paper quantifies a 23.4% decline in single-strand annealing repair efficiency in old cells, linked to prolonged G1-phase duration and high heteroduplex rejection.