MicrobiologybioRxivPreprint
Pyrimidine salvage in Toxoplasma gondii as a target for new treatment
H. A. A. Elati, A. L. Goerner, B. Martorelli di Genova…·H. P. De Koning
This paper identifies TgUUT1 as a key pyrimidine salvage transporter in Toxoplasma gondii and demonstrates that 5F-uracil derivatives are potent antiparasitic agents with efficacy comparable to sulfadiazine.
DOI 10.1101/2023.11.01.565095