Targeting MEK5 impairs non-homologous end-joining repair and sensitizes prostate cancer to DNA damaging agents
C. G. Broustas, A. J. Duval, K. R. Chaudhary, R. A. Friedman, R. K. Virk, H. B. Lieberman
This study shows that targeting MEK5 impairs NHEJ repair and enhances sensitivity of prostate cancer to DNA-damaging agents in vitro and in vivo.
bioRxiv · Aug 15, 2019Cancer Biology