Author

R. K. Virk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Califano· 1 shared A. J. Duval· 1 shared A. Z. Obradovic· 1 shared C. B. Anderson· 1 shared C. G. Broustas· 1 shared C. G. Drake· 1 shared C. R. Ager· 1 shared E. A. Lim· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Califano

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Author profile →

2 papers

Recent·Most cited

Single-Cell RNAseq Analysis Reveals Robust Anti-PD-1-Mediated Increase of Immune Infiltrate in Metastatic Castration-Sensitive Prostate Cancer

J. E. Hawley, A. Z. Obradovic, M. C. Dallos, E. A. Lim, K. Runcie, C. R. Ager, J. M. McKiernan, C. B. Anderson, G. J. Decastro, J. L. Weintraub, R. K. Virk, I. Lowy, J. Hu, M. G. Chaimowitz, X. V. Guo, , C. G. Drake

The paper analyzes single-cell RNAseq data from metastatic castration-sensitive prostate cancer patients treated with anti-PD-1 immunotherapy, showing increased immune infiltrate and identifying therapy-resistant tumor subpopulations and druggable targets.

bioRxiv · May 6, 2022 · PreprintCancer Biology

Targeting MEK5 impairs non-homologous end-joining repair and sensitizes prostate cancer to DNA damaging agents

C. G. Broustas, A. J. Duval, K. R. Chaudhary, R. A. Friedman, R. K. Virk, H. B. Lieberman

This study shows that targeting MEK5 impairs NHEJ repair and enhances sensitivity of prostate cancer to DNA-damaging agents in vitro and in vivo.

bioRxiv · Aug 15, 2019Cancer Biology