Author

H. D. Welhaven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 6 Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

R. K. June· 6 shared B. Bothner· 3 shared A. H. Welfley· 2 shared A. K. Hahn· 2 shared S. T. Walk· 2 shared A. Bergstrom· 1 shared A. Hahn· 1 shared A. R. Bergstrom· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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6 shared papersBiochemistry

R. K. June

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Author profile →

6 papers

Recent·Most cited

Metabolomic Profiles and Pathways in Osteoarthritic Human Cartilage: A Comparative Analysis with Healthy Cartilage

H. D. Welhaven, A. H. Welfley, P. Brahmachary, A. Bergstrom, E. Houske, M. Glimm, B. Bothner, A. Hahn, R. K. June

This study compares metabolomic profiles of healthy and osteoarthritic human cartilage to identify disease-associated metabolic endotypes and pathways.

bioRxiv · Jan 25, 2024Biochemistry

Metabolomic Profiling to Identify Early Urinary Biomarkers and Metabolic Pathway Alterations in Autosomal Dominant Polycystic Kidney Disease

A. K. Hahn, E. A. Houske, M. G. Glimm, A. R. Bergstrom, S. K. Slipher, H. D. Welhaven, M. C. Greenwood, G. M. Linse, R. K. June, A. S. L. Yu, D. P. Wallace

This study identifies metabolic pathway alterations and candidate biomarkers in early-stage ADPKD using metabolomic profiling of urine samples.

American Journal of Physiology-Renal Physiology · Jun 1, 2023Peer-reviewedBiochemistry

Metabolomic Phenotypes Reflect Patient Sex and Injury Status: A Cross-Sectional Analysis of Human Synovial Fluid

H. D. Welhaven, A. H. Welfley, P. Pershad, J. Satalich, R. O'Connell, B. Bothner, A. R. Vap, R. K. June

This study identifies distinct metabolomic profiles in synovial fluid associated with knee injury types and patient sex, suggesting metabolic differences linked to post-traumatic osteoarthritis development.

bioRxiv · Feb 3, 2023 · PreprintBioengineering

The cortical bone metabolome of C57BL/6J mice is sexually dimorphic

H. D. Welhaven, G. Vahidi, S. T. Walk, B. Bothner, S. A. Martin, C. M. Heveran, R. K. June

The study compares metabolomes of cortical bone, whole bone, and bone marrow in C57BL/6J mice, revealing sex differences and associations with bone strength.

bioRxiv · Aug 6, 2021Cell Biology

A comparison of shear- and compression-induced mechanotransduction in SW1353 chondrocytes

H. D. Welhaven, C. N. McCutchen, R. K. June

The paper compares shear- and compression-induced mechanotransduction in SW1353 chondrocytes using metabolomics to identify altered pathways.

bioRxiv · May 25, 2021 · PreprintBioengineering

The microbiome mediates subchondral bone loss and metabolomic changes after acute joint trauma

A. K. Hahn, C. W. Wallace, H. D. Welhaven, E. Brooks, M. McAlpione, B. A. Christiansen, S. T. Walk, R. K. June

This study compares the early joint injury responses in germ-free and conventional mice, finding that germ-free mice show less bone loss and distinct metabolic profiles linked to immune regulation.

bioRxiv · May 8, 2020Immunology