Characterizing the polarization continuum of macrophage subtypes M1, M2a and M2c
T. C. Oates, P. L. Moura, S. J. Cross, K. Roberts, H. E. Baum, K. Haydn-Smith, M. C. Wilson, K. J. Heesom, C. E. Severn, A. M. Toye
This study characterizes four macrophage subtypes using proteomics and functional assays, showing M2c macrophages upregulate pro-inflammatory markers and dexamethasone induces partial repolarization from M1 to M2c.
bioRxiv · Jun 13, 2022Immunology