Author

H. Fleury

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

a. gosselin· 1 shared A.-M. Mes-Masson· 1 shared B. Allard· 1 shared c. tumiotto· 1 shared D. Allard· 1 shared D. Provencher· 1 shared E. H. Ma· 1 shared F. Rodier· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

a. gosselin

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Author profile →

3 papers

Recent·Most cited

53BP1 mediates sensitivity to chemotherapy and is associated with poor clinical outcomes in high-grade serous ovarian cancer

M. Skulimowski, J. Bourbonnais, N. Malaquin, H. Fleury, I. Clement, L. Communal, K. Rahimi, D. Provencher, A.-M. Mes-Masson, F. Rodier

This study shows that high 53BP1 levels in ovarian cancer are linked to poor survival and chemotherapy resistance, suggesting it could be a therapeutic target.

bioRxiv · Sep 30, 2023 · PreprintCancer Biology

The CD73 immune checkpoint promotes tumor cell metabolic fitness

D. Allard, I. Cousineau, E. H. Ma, B. Allard, Y. Bareche, H. Fleury, J. Stagg

This study identifies CD73 as a metabolic regulator in tumor cells, showing it enhances mitochondrial respiration and aspartate biosynthesis, and that targeting CD73 reduces metabolic fitness and genomic stability.

eLife · Jun 1, 2023Peer-reviewedCancer Biology

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in patients receiving antiretroviral therapy: a study from Provir/Latitude45 project.

p. recordon pinson, c. tumiotto, p. bellecave, f. salin, p. thebault, a. gosselin, p. ancuta, m. soares, j.-p. routy, h. fleury

The paper compares HIV-1 proviral DNA sequences in blood and gut-associated lymphoid tissue in ART-treated patients, finding low intra-patient divergence and similar CTL epitope profiles between compartments.

bioRxiv · May 5, 2020Microbiology