13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells
E. H. Ma, M. S. Dahabieh, L. M. DeCamp, I. Kaymak, S. M. Kitchen-Goosen, D. G. Roy, M. J. Verway, R. M. Johnson, B. Samborska, C. A. Scullion, M. Steadman, M. Vos, T. P. Roddy, C. M. Krawczyk, K. S. Williams, , R. G. Jones
This study uses 13C-labeled metabolites to show CD8+ T cells switch from glutamine to acetate metabolism during infection.
bioRxiv · Jun 9, 2023 · PreprintImmunology