Author

H. Gulbudak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:statistical model· 4 Approach:mechanistic / dynamical model· 2 Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. C. Macdonald· 2 shared A. Jolles· 1 shared A. Nandi· 1 shared B. Beechler· 1 shared E. Gorsich· 1 shared E. Perez-Martin· 1 shared G. Li· 1 shared H. Ryu· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

J. C. Macdonald

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Author profile →

5 papers

Recent·Most cited

Robust parameterization of a viral-immune kinetics model for sequential Dengue virus (DENV) infections with Antibody-Dependent Enhancement (ADE)

J. C. Macdonald, H. Gulbudak

This study parameterizes a viral-immune kinetics model for sequential Dengue infections, showing that initial IgG antibody concentration explains differences in infection severity and estimating the half-life of Dengue IgG antibodies.

bioRxiv · Aug 29, 2023 · PreprintImmunology

Within-host viral growth and immune response rates predict FMDV transmission dynamics for African Buffalo

J. C. Macdonald, H. Gulbudak, B. Beechler, E. Gorsich, S. Gubbins, E. Perez-Martin, A. Jolles

The paper links within-host viral growth and immune response rates to FMDV transmission dynamics in African buffalo, showing immune activation rates determine viral fitness and transmission.

bioRxiv · Dec 2, 2022Ecology

Investigating the impact of combination phage and antibiotic therapy: a modeling study

S. Banuelos, H. Gulbudak, M. A. Horn, Q. Huang, A. Nandi, H. Ryu, R. Segal

This study uses a mathematical model to examine how immune responses affect phage-antibiotic combination therapy and finds that treatment frequency and dose are critical for effectiveness.

bioRxiv · Jan 8, 2020 · PreprintMicrobiology

Viral Invasion Fitness Across a Continuum from Lysis to Latency

J. S. Weitz, G. Li, H. Gulbudak, M. H. Cortez, R. J. Whitaker

The paper introduces a cell-centric metric to quantify viral invasion fitness, showing that strategies like lysogeny can outperform lytic strategies under certain conditions.

Virus Evolution · Apr 22, 2019Peer-reviewedEcology

Heterogeneous Viral Strategies Promote Coexistence in Virus-Microbe Systems

H. Gulbudak, J. Weitz

The paper models lytic and chronic viral strategies in virus-microbe systems and finds that chronic viruses can require lytic viruses for survival and invasion.

bioRxiv · Apr 7, 2018Ecology