Author

S. Gubbins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Ecology· 2 Immunology· 2 Zoology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 8 Approach:experimental assay· 6 Organism:chicken / avian· 4 Approach:statistical model· 4 Organism:plant (other)· 3 Organism:Arabidopsis· 2 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

B. Charleston· 3 shared C. Batten· 3 shared A. Jolles· 2 shared A. McNee· 2 shared B. Beechler· 2 shared B. Paudyal· 2 shared E. Perez-Martin· 2 shared E. Tchilian· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersImmunology

B. Charleston

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Quantifying the relationship between within-host dynamics and transmission for viral diseases of livestock

S. Gubbins

The paper links within-host viral dynamics to between-host transmission using a phenomenological model, testing it with data from foot-and-mouth disease and swine influenza.

bioRxiv · May 5, 2023Microbiology

The mechanical arthropod vector Stomoxys calcitrans influences the outcome of lumpy skin disease virus infection in cattle

C. G. Cook, H. Munyanduki, P. C. Fay, N. Wijesiriwardana, K. Moffat, S. Gubbins, S. Armstrong, C. Batten, I. Dietrich, D. R. Greaves, K. Darpel, P. M. Beard

This study investigates how the mechanical transmission of lumpy skin disease virus (LSDV) by the stable fly Stomoxys calcitrans affects disease progression in cattle, finding that saliva and bite trauma accelerate disease kinetics.

bioRxiv · Mar 13, 2023 · PreprintMicrobiology

Within-host viral growth and immune response rates predict FMDV transmission dynamics for African Buffalo

J. C. Macdonald, H. Gulbudak, B. Beechler, E. Gorsich, S. Gubbins, E. Perez-Martin, A. Jolles

The paper links within-host viral growth and immune response rates to FMDV transmission dynamics in African buffalo, showing immune activation rates determine viral fitness and transmission.

bioRxiv · Dec 2, 2022Ecology

Inferring transmission routes for foot-and-mouth disease virus within a cattle herd using approximate Bayesian computation

J. Ellis, E. Brown, C. Colenutt, D. Schley, S. Gubbins

This study uses approximate Bayesian computation to infer transmission routes of FMDV within a cattle herd, finding direct contact contributes most infections but environmental contamination also plays a role.

bioRxiv · Oct 14, 2022Zoology

Viral dynamics and immune responses to foot-and-mouth disease virus in African buffalo (Syncerus caffer).

E. Perez-Martin, B. Beechler, K. Scott, L.-M. de Klerk-Lorist, F. Zhang, G. Limon, B. Dugovich, S. Gubbins, A. Botha, N. Juleff, R. Hetem, L. van Schalkwyk, F. Maree, A. Jolles, B. Charleston

This study investigates FMD virus dynamics and immune responses in African buffalo, showing systemic infection, high viral loads, and strong immune responses despite mild clinical symptoms.

bioRxiv · Nov 24, 2021Zoology

Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells.

V. Martini, M. Edmans, S. Gubbins, S. Jayaraman, B. Paudyal, S. Morgan, A. McNee, T. Morin, P. Rijal, W. Gerner, A. K. Sewell, R. Inoue, M. Bailey, T. Connelley, B. Charleston, , E. Tchilian

The paper identifies and characterizes influenza NP-specific CD8 T cells in porcine tissues, showing their persistence and gene expression changes in the lung.

bioRxiv · Aug 23, 2021Immunology

Natural reassortment of a segmented RNA arbovirus illustrates plasticity of phenotype in the arthropod vector and mammalian host in vivo

C. J. Sanders, E. Veronesi, P. Z. Rajko-Nenow, P. P. C. Mertens, C. Batten, S. Gubbins, K. E. Darpel, S. Carpenter

This study investigates reassortment in bluetongue virus, showing how it affects vector competence and virulence in natural settings.

bioRxiv · Aug 9, 2021 · PreprintMicrobiology

Inferring within-flock transmission dynamics of highly pathogenic avian influenza (H5N8) in France, 2020

T. Vergne, S. Gubbins, C. Guinat, B. Bauzile, M. Delpont, D. Chakraborty, H. Gruson, B. Roche, M. Andraud, M. Paul, J.-L. Guerin

This study uses a stochastic epidemic model and ABC-SMC to estimate H5N8 transmission dynamics in ducks, revealing key parameters and latent threats in France in 2020.

bioRxiv · Dec 21, 2020Ecology

Magnitude and kinetics of T cell and antibody responses during H1N1pdm09 infection in outbred and inbred Babraham pigs

M. Edmans, A. Mcnee, E. Porter, E. Vatzia, B. Paudyal, V. Martini, S. Gubbins, O. Francis, R. Harley, A. Thomas, R. Burt, S. Morgan, A. Fuller, A. Sewell, B. Charleston, , E. Tchilian

This study compares T cell and antibody responses to H1N1pdm09 infection in inbred and outbred pigs, showing similar immune responses despite differences in genetic background.

bioRxiv · Oct 28, 2020Immunology

Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disease outbreaks.

B. Sanz-Bernardo, I. R. Haga, N. Wijesiriwardana, S. Basu, W. Larner, A. V. Diaz, Z. Langlands, E. Denison, J. Stoner, M. White, C. Sanders, P. C. Hawes, A. J. Wilson, J. Atkinson, C. Batten, , P. M. Beard

This study quantifies LSDV acquisition and retention by vector insects and models transmission, finding clinical cattle are key promoters of viral spread and highlighting the need for targeted control strategies.

bioRxiv · Jun 18, 2020Microbiology