Author

H. J. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. E. Turk· 3 shared D. A. Calderwood· 2 shared A. Daniels· 1 shared A. Iwasaki· 1 shared B. Akiyoshi· 1 shared B. E. E. Turk· 1 shared C. Calderwood· 1 shared C. Song· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCell Biology

B. E. Turk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An unconventional regulatory circuitry involving Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes

D. Ballmer, H. J. Lou, M. Ishii, B. E. Turk, B. Akiyoshi

This study shows that Aurora B and KKT14 form an unconventional regulatory pathway controlling mitotic exit and chromosome segregation in trypanosomes.

bioRxiv · Jan 20, 2024 · PreprintCell Biology

Setdb1-loss induces type-I interferons and immune clearance of melanoma

M. K. McGeary, W. Damsky, A. Daniels, E. Song, G. Micevic, C. Calderwood, H. J. Lou, S. Paradkar, S. Kaech, D. A. Calderwood, B. E. Turk, A. Iwasaki, M. W. Bosenberg

This study identifies Setdb1 loss as a driver of type-I interferon signaling and immune clearance of melanoma through ERV activation and CD8+ T-cell infiltration.

bioRxiv · May 23, 2023Cancer Biology

Proteome-wide screening for mitogen-activated protein kinase docking motifs and interactors

G. Shi, J. Torres Robles, C. Song, L. Salichos, H. J. Lou, M. Gerstein, B. E. Turk

The paper screens for MAPK docking motifs and interactors using a yeast-based genetic pipeline, identifying novel sequences and residues critical for binding to JNK1 and p38.

bioRxiv · Aug 20, 2021Cell Biology

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

E. Cho, H. J. Lou, L. Kuruvilla, D. A. Calderwood, B. E. E. Turk

This study identifies PPP6C as a MEK phosphatase that negatively regulates ERK signaling by dephosphorylation, with implications for melanoma therapy resistance.

bioRxiv · Sep 18, 2020Cancer Biology