Galectin-9 has non-apoptotic cytotoxic activity towards Acute Myeloid Leukemia independent of cytarabine resistance
G. Choukrani, N. Visser, N. Ustyanovska Avtenyuk, M. Olthuis, G. Marsman, E. Ammatuna, H. J. Lourens, T. Niki, G. Huls, E. Bremer, V. R. Wiersma
This study shows Galectin-9 induces non-apoptotic cytotoxicity in AML cells, including resistant ones, and enhances the effect of Azacytidine.
bioRxiv · Jan 12, 2023Cancer Biology