Oncogenic RAS instructs morphological transformation of human epithelia via differential tissue mechanics.
A. Nyga, J. Munoz, S. Dercksen, G. Fornabaio, M. Uroz, X. Trepat, B. Baum, H. K. Matthews, V. Conte
This study shows that oncogenic RAS causes morphological changes in human epithelial tissues through differential mechanics, leading to three-dimensional structures similar to cancer behaviors.
bioRxiv · Jan 19, 2021Cancer Biology