Prediction of broad chemical toxicities using induced pluripotent stem cells and gene networks by transfer learning from embryonic stem cell data
J. Yamane, T. Wada, H. Otsuki, K. Inomata, M. Suzuki, T. Hisaki, S. Sekine, H. Kouzuki, K. Kobayashi, H. Sone, J. K. Yamashita, M. Osawa, M. K. Saito, W. Fujibuchi
This paper predicts chemical toxicities using induced pluripotent stem cells and gene networks via transfer learning from embryonic stem cell data, achieving high accuracy across multiple toxicity categories.
bioRxiv · Nov 5, 2021 · PreprintPharmacology & Toxicology