Author

H. L. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Kang· 2 shared B. Coventry· 2 shared D. Baker· 2 shared J. Dauparas· 2 shared A. Bera· 1 shared A. Courbet· 1 shared A. H.-W. Yeh· 1 shared A. J. Borst· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

A. Kang

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2 papers

Recent·Most cited

Small-molecule binding and sensing with a designed protein family

G. R. Lee, S. J. Pellock, C. Norn, D. Tischer, J. Dauparas, I. Anishchenko, J. A. M. Mercer, A. Kang, A. Bera, H. Nguyen, I. Goreshnik, D. Vafeados, N. Roullier, H. L. Han, B. Coventry, , D. Baker

This paper designs a protein family that binds and senses small molecules using deep learning and physics-based methods, achieving nanomolar sensitivity for cortisol.

bioRxiv · Nov 1, 2023Biochemistry

Blueprinting expandable nanomaterials with standardized protein building blocks

T. F. Huddy, Y. Hsia, R. D. Kibler, J. Xu, N. Bethel, D. Nagarajan, R. Redler, P. J. Y. Leung, A. Courbet, E. C. Yang, A. K. Bera, N. Coudray, S. J. Calise, F. A. Davila-Hernandez, C. Weidle, , D. Baker

This paper introduces standardized protein building blocks and geometric design principles to create expandable protein nanomaterials, validated through X-ray crystallography and electron microscopy.

bioRxiv · Jun 9, 2023Biochemistry