Author

R. D. Kibler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:protein design· 2 Research Focus:protein folding & dynamics· 2 Assay:electronic health records· 1

Frequent Co-Authors

D. Baker· 4 shared A. Courbet· 2 shared A. J. Borst· 2 shared A. K. Bera· 2 shared A. Kang· 2 shared B. I. M. Wicky· 2 shared B. L. Stoddard· 2 shared J. Dauparas· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBiochemistry

D. Baker

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Author profile →

4 papers

Recent·Most cited

Design of four component T=4 tetrahedral, octahedral, and icosahedral protein nanocages through programmed symmetry breaking

S. Lee, R. D. Kibler, Y. Hsia, A. J. Borst, A. Philomin, M. A. Kennedy, B. L. Stoddard, D. Baker

The paper designs T=4 protein nanocages with tetrahedral, octahedral, and icosahedral symmetries using pseudo-symmetrization of trimeric building blocks, resulting in structures with distinct subunits and interfaces.

bioRxiv · Jun 16, 2023 · PreprintBiochemistry

Blueprinting expandable nanomaterials with standardized protein building blocks

T. F. Huddy, Y. Hsia, R. D. Kibler, J. Xu, N. Bethel, D. Nagarajan, R. Redler, P. J. Y. Leung, A. Courbet, E. C. Yang, A. K. Bera, N. Coudray, S. J. Calise, F. A. Davila-Hernandez, C. Weidle, , D. Baker

This paper introduces standardized protein building blocks and geometric design principles to create expandable protein nanomaterials, validated through X-ray crystallography and electron microscopy.

bioRxiv · Jun 9, 2023Biochemistry

Stepwise design of pseudosymmetric protein hetero-oligomers

R. D. Kibler, S. Lee, M. A. Kennedy, B. I. M. Wicky, S. M. Lai, M. M. Kostelic, X. Li, C. M. Chow, L. Carter, V. H. Wysocki, B. L. Stoddard, D. Baker

The paper introduces a method to design pseudosymmetric protein hetero-oligomers by redesigning symmetric homo-oligomers and recombining them to form new hetero-oligomers with high structural specificity.

bioRxiv · Apr 7, 2023 · PreprintBiochemistry

Hallucinating protein assemblies

B. I. M. Wicky, L. F. Milles, A. Courbet, R. J. Ragotte, J. Dauparas, E. Kinfu, S. Tipps, R. D. Kibler, M. Baek, F. DiMaio, X. Li, L. Carter, A. Kang, H. Nguyen, A. K. Bera, D. Baker

Deep network-based protein design generates symmetric homo-oligomers with high structural accuracy, demonstrating the potential for creating novel nanomachines and biomaterials.

Science · Oct 7, 2022Peer-reviewedBiophysics