Author

H. Ong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Jackson· 1 shared A. Romero Ramirez· 1 shared A. Shilton· 1 shared B. K. Ganser-Pornillos· 1 shared C. Brandt· 1 shared C. Crosnier· 1 shared C. Duffy· 1 shared C. Tolley· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. Jackson

Mutual co-authors in cluster

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3 papers

Recent·Most cited

An invariant Trypanosoma vivax vaccine antigen inducing protective immunity

D. Autheman, C. Crosnier, S. Clare, D. Goulding, C. Brandt, K. Harcourt, C. Tolley, F. Galaway, M. Khushu, H. Ong, A. Romero Ramirez, C. Duffy, A. Jackson, G. J. Wright

This study identifies an invariant Trypanosoma vivax antigen that induces protective immunity through vaccination and monoclonal antibodies.

bioRxiv · Feb 10, 2021Microbiology

Poly(ADP-ribose) potentiates ZAP antiviral activity

O. Pornillos, G. Xue, K. Braczyk, D. Goncalves-Carneiro, H. Ong, D. M. Dawidziak, K. Zawada, W. Yueping, K. K. Zadrozny, B. K. Ganser-Pornillos, P. D. Bieniasz

This study shows that poly(ADP-ribose) enhances ZAP's ability to degrade viral RNA by binding to ZAP's WWE domains, improving its antiviral activity against HIV-1.

bioRxiv · Dec 17, 2020Microbiology

Origin and evolution of the Zinc Finger Antiviral Protein

D. Goncalves Carneiro, M. A. Takata, H. Ong, A. Shilton, P. D. D. Bieniasz

This paper traces the molecular evolution of ZAP, showing its origin from an ancestral gene and its adaptation to target viral RNA through CpG specificity and co-factor TRIM25 dependence.

bioRxiv · Dec 4, 2020Microbiology