Distinct cell states define the developmental trajectories of mucinous appendiceal neoplasms towards pseudomyxoma metastases
C. Ayala, A. Sathe, X. Bai, S. M. Grimes, J. Shen, G. A. Poultsides, B. Lee, H. P. Ji
This study uses single-cell RNA-sequencing to identify distinct cell states in appendiceal mucinous neoplasms and their progression to pseudomyxoma peritonei, revealing developmental trajectories and signaling pathway changes.
bioRxiv · May 26, 2022 · PreprintCancer Biology