Author

G. Poultsides

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sathe· 3 shared B. T. Lau· 2 shared C. Suarez· 2 shared H. Ji· 2 shared S. M. Grimes· 2 shared X. Bai· 2 shared A. Shelton· 1 shared A. Su· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

A. Sathe

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GITR and TIGIT immunotherapy provokes divergent multi-cellular responses in the tumor microenvironment of gastrointestinal cancers

A. Sathe, C. Ayala, X. Bai, S. M. Grimes, B. Lee, C. Kin, A. Shelton, G. Poultsides, H. Ji

The paper examines GITR and TIGIT immunotherapies in gastrointestinal cancers using ex vivo cultures and single-cell sequencing to identify their cellular mechanisms in the tumor microenvironment.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated SPP1+ macrophages and fibroblasts

A. Sathe, K. Mason, S. M. Grimes, Z. Zhou, B. T. Lau, X. Bai, A. Su, X. Tan, H. Lee, C. Suarez, Q. Nguyen, G. Poultsides, N. Zhang, H. P. Ji

This paper identifies SPP1+ macrophages and fibroblasts in liver metastatic CRC TME that form immunosuppressive networks, promoting tumor growth and poor prognosis.

bioRxiv · Sep 1, 2020Cancer Biology

Single cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment

A. Sathe, S. Grimes, B. T. Lau, J. Chen, C. Suarez, R. Huang, G. Poultsides, H. Ji

This study uses single-cell RNA sequencing to analyze gastric cancer tumor microenvironment, identifying reprogramming in immune and stromal cells and novel molecular targets for immunotherapy.

bioRxiv · Oct 1, 2019Cancer Biology