Author

C. Ayala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Sathe· 2 shared B. Lee· 2 shared S. M. Grimes· 2 shared X. Bai· 2 shared A. Kandasamy· 1 shared A. Shelton· 1 shared C. Kin· 1 shared G. A. Poultsides· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

A. Sathe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GITR and TIGIT immunotherapy provokes divergent multi-cellular responses in the tumor microenvironment of gastrointestinal cancers

A. Sathe, C. Ayala, X. Bai, S. M. Grimes, B. Lee, C. Kin, A. Shelton, G. Poultsides, H. Ji

The paper examines GITR and TIGIT immunotherapies in gastrointestinal cancers using ex vivo cultures and single-cell sequencing to identify their cellular mechanisms in the tumor microenvironment.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Distinct cell states define the developmental trajectories of mucinous appendiceal neoplasms towards pseudomyxoma metastases

C. Ayala, A. Sathe, X. Bai, S. M. Grimes, J. Shen, G. A. Poultsides, B. Lee, H. P. Ji

This study uses single-cell RNA-sequencing to identify distinct cell states in appendiceal mucinous neoplasms and their progression to pseudomyxoma peritonei, revealing developmental trajectories and signaling pathway changes.

bioRxiv · May 26, 2022 · PreprintCancer Biology

A balance between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3-D matrices

J. Francois, A. Kandasamy, Y.-T. Yeh, C. Ayala, R. Meili, S. Chien, J. C. Lasheras, J. C. del Alamo

This study shows that neutrophils balance matrix deformation and turning to navigate 3-D collagen matrices, with myosin-II and Arp2/3 playing key roles in this process.

bioRxiv · Sep 2, 2020Biophysics