Author

H. Peacock

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

E. E. Blythe· 1 shared H. Suga· 1 shared K. M. Shokat· 1 shared M. von Zastrow· 1 shared Q. Hu· 1 shared R. Gao· 1 shared S. A. Dai· 1 shared Z. Zhang· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

E. E. Blythe

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1 paper

Recent·Most cited

State-selective Modulation of Heterotrimeric Gαs Signaling with Macrocyclic Peptides

S. A. Dai, Q. Hu, R. Gao, H. Peacock, E. E. Blythe, Z. Zhang, M. von Zastrow, H. Suga, K. M. Shokat

This study identifies two macrocyclic peptides that selectively modulate active and inactive states of Gs, offering a new approach for developing state-dependent GTPase inhibitors.

bioRxiv · Apr 25, 2020Biochemistry