Inhibition of glioblastoma cell proliferation and invasion by the choline-kinase inhibitor JAS239 varies with cell type and hypoxia
C. L. Kelly, M. Wydrzynska, M. M. Phelan, S. Osharovich, E. J. Delikatny, V. See, H. Poptani
This study evaluates how hypoxia affects the efficacy of the ChoK inhibitor JAS239 in GBM cells, showing variable responses across cell lines and metabolic pathway changes.
bioRxiv · Jan 17, 2024 · PreprintCancer Biology