ZIKV disrupts placental ultrastructure and drug transporter expression in mice
C. B. V. Andrade, V. R. S. Monteiro, S. V. A. Coelho, H. R. Gomes, R. P. C. Sousa, V. M. O. Nascimento, F. F. Bloise, S. G. Matthews, E. Bloise, L. B. Arruda, T. M. Ortiga-Carvalho
This study shows that ZIKV infection in pregnant mice causes placental structural damage and reduced drug transporter expression, leading to fetal growth restriction and increased fetal death rates.
bioRxiv · Dec 17, 2020Physiology