ImmunologybioRxiv
Lupus IgA1 autoantibodies synergize with IgG to enhance plasmacytoid dendritic cell responses to RNA-containing immune complexes
H. R. Waterman, M. J. Dufort, S. E. Posso…·J. A. Hamerman
The paper shows IgA1 autoantibodies enhance pDC IFN responses when combined with IgG in RNA-containing immune complexes through FcR receptor interaction.
DOI 10.1126/scitranslmed.adl3848