This study identifies HIF1A's role in recruiting primate-specific endogenous retroviruses into hypoxic and immune responses, revealing their regulatory impact on gene expression.

bioRxiv · Sep 1, 2026 · PreprintGenomics

A Cluster of Acidic Residues in the Cytoplasmic Domain of SARS-CoV-2 Spike is Required for Virion-Incorporation and Infectivity

Charlotte A. Stoneham, Rajendra Singh, Amalia De Leon, Petra Tafelmeyer, Francisco M. Acosta, Angus Fuori, Michael Anderson, Peter W. Ramirez, Hannah S. Sperber, Satish K. Pillai, Mary K. Lewinski, John Guatelli

This study identifies an acidic cluster motif in the SARS-CoV-2 Spike protein's cytoplasmic domain essential for virion incorporation and infectivity.

PLoS ONE · Mar 12, 2026Peer-reviewedMolecular Biology

P-BODY AND CYTOSKELETON REMODELING BY ORTHOHANTAVIRUSES.

H. S. Schwarzer-Sperber, Annett Petrich, Matthias Schade, Niklaas Nilson, Linah Chibrac-Ahad, Maik Joerg Lehmann, Katharina Paulick, Sabrina Weiß, Tina Dluzak, Daniel R. Bourquain, Peter T. Witkowski, Detlev H. Krüger, Andreas Herrmann, Roland Schwarzer

This study uses advanced imaging to analyze how orthohantaviruses alter P-bodies and the cytoskeleton during infection, revealing spatial correlations and degradation patterns of viral RNAs.

Journal of General Virology · Feb 12, 2026Peer-reviewedMicrobiology