Author

H. Sirkia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Houdusse· 2 shared C. Kikuti· 2 shared A. A. Mohammed Khalid· 1 shared A. Asenjo· 1 shared A. David· 1 shared A. Di Cicco· 1 shared A. El Marjou· 1 shared C. Delevoye· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

A. Houdusse

Mutual co-authors in cluster

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2 papers

Recent·Most cited

How Myosin VI Traps its Off-State, is Activated and Dimerizes

L. Canon, C. Kikuti, V. J. Planelles-Herrero, T. Lin, F. Mayeux, H. Sirkia, Y. i. Lee, L. Heidsieck, L. Velikovsky, A. David, X. Liu, D. Moussaoui, E. Forest, P. Hook, K. J. Petersen, , A. Houdusse

This study investigates how Myosin VI is trapped in its off-state, activated, and dimerizes through structural and functional analyses of its interactions with partners.

bioRxiv · Jun 30, 2023Biochemistry

Nucleotide-free structures of Kif20A illuminate the atypical allostery in this mitotic kinesin-6

F. M. Ranaivoson, V. Crozet, M. Benoit, A. A. Mohammed Khalid, C. Kikuti, H. Sirkia, A. El Marjou, A. Asenjo, H. Sosa, C. Schmidt, S. Rosenfeld, A. Houdusse

This paper presents the first high-resolution structure of Kif20A's motor domain, revealing structural features and allostery mechanisms that explain its atypical motility and ATPase activity.

bioRxiv · Nov 10, 2022 · PreprintBiochemistry