Author

C. Kikuti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Houdusse· 4 shared D. Moussaoui· 2 shared H. Sirkia· 2 shared A. A. Mohammed Khalid· 1 shared A. Asenjo· 1 shared A. David· 1 shared A. Di Cicco· 1 shared A. El Marjou· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBiochemistry

A. Houdusse

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

How Myosin VI Traps its Off-State, is Activated and Dimerizes

L. Canon, C. Kikuti, V. J. Planelles-Herrero, T. Lin, F. Mayeux, H. Sirkia, Y. i. Lee, L. Heidsieck, L. Velikovsky, A. David, X. Liu, D. Moussaoui, E. Forest, P. Hook, K. J. Petersen, , A. Houdusse

This study investigates how Myosin VI is trapped in its off-state, activated, and dimerizes through structural and functional analyses of its interactions with partners.

bioRxiv · Jun 30, 2023Biochemistry

Cryo-EM structure of the folded-back state of human β-cardiac myosin

A. Grinzato, D. Auguin, C. Kikuti, N. Nandwani, D. Moussaoui, D. Pathak, E. Kandiah, K. M. Ruppel, J. A. Spudich, A. Houdusse, J. Robert-Paganin

The paper reports the 3.6 Å cryo-EM structure of the folded-back IHM state of human β-cardiac myosin, revealing HCM mutation hotspots and structural differences from smooth muscle myosin IHMs.

bioRxiv · Apr 15, 2023 · PreprintBiophysics

Nucleotide-free structures of Kif20A illuminate the atypical allostery in this mitotic kinesin-6

F. M. Ranaivoson, V. Crozet, M. Benoit, A. A. Mohammed Khalid, C. Kikuti, H. Sirkia, A. El Marjou, A. Asenjo, H. Sosa, C. Schmidt, S. Rosenfeld, A. Houdusse

This paper presents the first high-resolution structure of Kif20A's motor domain, revealing structural features and allostery mechanisms that explain its atypical motility and ATPase activity.

bioRxiv · Nov 10, 2022 · PreprintBiochemistry

Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth

L. K. Krüger, M. Gelin, L. Ji, C. Kikuti, A. Houdusse, M. Thery, L. Blanchoin, P. Tran

This study identifies Klp9's dual role in regulating microtubule sliding and growth during anaphase B spindle elongation in S. pombe.

bioRxiv · Feb 17, 2021Cell Biology