Investigation of heterochromatin protein 1 function in the malaria parasite Plasmodium falciparum using a conditional domain deletion and swapping approach
H. T. N. Bui, A. Passecker, N. M. B. Brancucci, T. S. Voss
This study investigates PfHP1 domains in Plasmodium falciparum using CRISPR/Cas9 and DiCre/LoxP, showing their roles in nuclear targeting, heterochromatin formation, and parasite proliferation.
bioRxiv · Nov 26, 2020Microbiology